What are Pseudo Tablets?

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May 27, 2026 | Elyxr's Blog

Mitragynine pseudoindoxyl, usually shortened to MGPI and also called “Pseudo,” has been a temporary Schedule I controlled substance in the United States since August 26, 2026. Right now that control applies at any amount.

On October 14, 2026, DEA proposed a change: control MGPI only above a set threshold. That proposal has not taken effect. This guide explains the rule in force today, what the proposal would do, and what it does not do.

Elyxr does not sell Pseudo products.

Pseudo (MGPI) at a glance

Federal status today Temporary Schedule I at any amount (Federal Register 2026-17429)
In effect since August 26, 2026
Current order ends August 26, 2028, unless extended, replaced or made permanent
Pending change DEA notice of October 14, 2026 proposes control above a threshold (Federal Register 2026-20943)
Earliest date the change can take effect On or after November 13, 2026, on the day an order publishes
Approved medical use None (FR 2026-17429)
Last verified October 21, 2026

What is mitragynine pseudoindoxyl?

Mitragynine pseudoindoxyl is a compound related to the alkaloids in kratom. The federal scheduling order describes it as “a chemical rearrangement product of 7-hydroxymitragynine” and says the products on the market were made through synthetic modification of purified mitragynine or 7-OH, not taken from the plant as it grows (FR 2026-17429). The order notes that the compound was first mentioned in scientific literature in 1974.

So while mitragynine pseudoindoxyl is linked to kratom chemistry, products labeled “Pseudo” are not kratom leaf.

How Pseudo products were marketed

According to the federal order (FR 2026-17429), MGPI products were sold:

  • as powders, tablets and liquid shots, often as flavored chewables;
  • online and in gas stations, corner shops and vape shops;
  • under labels such as “botanical extracts” or “for laboratory, botanical, and research purposes only.”

The rule in force today: Schedule I at any amount

The August 26, 2026 order sets no minimum. Any product that contains MGPI is a Schedule I product, whatever else it contains and whatever the label says (FR 2026-17429).

Schedule I is the most restrictive federal category: substances with no currently accepted medical use and a high potential for abuse (DEA: Drug Scheduling). Making, selling or possessing them outside DEA-registered research is a federal offense (21 U.S.C. 841; 21 U.S.C. 844).

What the October 14, 2026 proposal would change

HHS sent DEA a new recommendation by letter dated October 8, 2026 (FR 2026-20943). Based on it, DEA withdrew its July 6, 2026 notice for 7-OH (FR 2026-13580) and published a new notice covering both 7-OH and MGPI (FR 2026-20943).

Under the proposal, a product would be Schedule I if it contains 7-OH or MGPI (alone or combined):

  • above 1 milligram per gram, for solid products; or
  • above 1 milligram per milliliter, for liquid products; or
  • at a mitragynine-to-target ratio below 100 to 1.

DEA explains that these compounds can occur in trace amounts in some botanical kratom products, which is why it chose a threshold rather than a flat ban. It also says no one should infer that products below the threshold are safe (FR 2026-20943).

What the proposal does not do

  • It does not change anything today. Until a new order publishes, MGPI stays Schedule I at any amount.
  • It does not make a product legal because of its name. Any product above the threshold would be Schedule I, whatever its label says.
  • It does not take effect gradually. A temporary order takes effect on the day it publishes, which can be on or after November 13, 2026 (FR 2026-20943).

The Department of Justice summarized the change in a press release (DOJ press release).

“Pseudo + MIT” and other blends

Blends that combine MGPI with mitragynine (often labeled “MIT”) are covered by the current order because they contain MGPI. Under the current order, any product containing MGPI is Schedule I, whatever else it contains.

State law

Federal Schedule I status applies in every state. Florida also added seven 7-OH related compounds, including MGPI and MGM-15, to its own Schedule I by emergency rule on June 22, 2026 (Florida Phoenix).

MGPI has also been found in products that did not name it. In July 2026, Utah testing found MGPI and MGM-15 in tablets labeled cat’s claw (Utah Department of Agriculture and Food), and Utah officials later linked four deaths to mislabeled cat’s claw products (TownLift).

Timeline

Date What happened Source
June 22, 2026 Florida emergency rule adds seven 7-OH related compounds, including MGPI, to state Schedule I Florida Phoenix
July 6, 2026 DEA notice of intent for 7-OH published (later withdrawn) FR 2026-13580
August 26, 2026 Temporary Schedule I order for MGPI, MGM-15 and MGM-16 takes effect FR 2026-17429
October 14, 2026 New DEA notice proposes a threshold for 7-OH and MGPI FR 2026-20943
On or after November 13, 2026 An order based on the new notice can publish and takes effect that day FR 2026-20943

Frequently asked questions

Is Pseudo legal?

No. Mitragynine pseudoindoxyl has been a temporary Schedule I controlled substance at any amount since August 26, 2026 (FR 2026-17429).

Does the October 2026 threshold notice change Pseudo’s status today?

No. It is a proposal. MGPI stays Schedule I at any amount until DEA publishes a new order, which can happen on or after November 13, 2026 (FR 2026-20943).

Is Pseudo the same as 7-OH?

No. They are different compounds. Both appear in the October 14, 2026 notice, but only MGPI is controlled today. See federal status compared.

Is mitragynine pseudoindoxyl natural?

The federal order says the products on the market were made through synthetic modification of purified kratom alkaloids. Trace amounts can occur in some botanical kratom products, which is why DEA proposed a threshold.

Are “Pseudo + MIT” blends legal?

No. Any product containing MGPI is Schedule I under the current order, whatever else it contains.

Does Elyxr sell Pseudo?

No. Elyxr does not sell Pseudo products.

Related reading

Sources

  1. Federal Register 2026-17429, temporary Schedule I order for MGPI, MGM-15 and MGM-16 (Aug 26, 2026) (checked October 21, 2026)
  2. Federal Register 2026-20943, DEA notice of intent for 7-OH and MGPI above a threshold (Oct 14, 2026) (checked October 21, 2026)
  3. DEA: Drug Scheduling (checked October 21, 2026)
  4. 21 U.S.C. 841, manufacture and distribution (Cornell LII) (checked October 21, 2026)
  5. 21 U.S.C. 844, possession (Cornell LII) (checked October 21, 2026)
  6. Federal Register 2026-13580, DEA notice of intent for 7-OH (Jul 6, 2026) (checked October 21, 2026)
  7. U.S. Department of Justice press release on the 7-OH and related scheduling actions (Oct 2026) (checked October 21, 2026)
  8. Florida Phoenix: Florida emergency rule adds 7-OH related compounds to Schedule I (Jun 22, 2026) (checked October 21, 2026)
  9. Utah Department of Agriculture and Food: illegal kratom product sold as cat’s claw (Jul 30, 2026) (checked October 21, 2026)
  10. TownLift: Utah officials renew warning after four deaths linked to mislabeled cat’s claw products (Oct 7, 2026) (checked October 21, 2026)

This article explains public government records in plain language. It is general information, not legal advice. Laws change quickly in this area, so check the linked sources and your own state’s rules before you act. Last verified: October 21, 2026.